邓宁 博士，教授，博士研究生导师，美国密西根大学博士后。暨南大学生科院细胞工程教研室主任，广东省抗体药物与免疫检测工程技术研究中心主任，广东省免疫学会常务理事。国家“863”项目主持人，国家自然科学基金等项目评审专家， 暨南大学“十一五”优秀科研工作者，暨南大学生科院师德标兵。

 主要围绕肿瘤血管新生抑制机理、肿瘤治疗性多肽疫苗、肿瘤治疗相关的工程抗体与抗体药物开发等开展研究。建立了肿瘤血管生长抑制、肿瘤生长转移等评价系统，建立了和肿瘤多肽疫苗的设计和人源性抗体药物研究技术平台。开发的人源性抗bFGF抗体肿瘤抑制率高达80%。开发的多表位肿瘤治疗性疫苗已进入临床前研究。主持了国家“863”专题项目、国家自然科学基金，教育部科学技术研究重点项目，广东省科技公共和广州市科技攻关重点项目等科多项研项目。获批科研项目经费800多万元。获得国际发明专利授权1项，获得国家发明专利授权7项。在国内外学术期刊发表研究论文80 余篇。

  主编《动物细胞工程》，科学出版社，2014，科学出版社“十二五”规划教材，副主编教材《细胞工程原理与技术》，高等教育出版社，2017，iCourse系列教材。参编《医学细胞生物学》科学出版社2011，参编《医学细胞生物学实验与复习思考题》，科学出版社2012。主持“动物细胞工程”广东省精品资源共享课程。指导本科学生获批广东省挑战杯大学生科技作品竞赛三等奖，指导本科学生获批国家级创新工程项目5项。主讲动物细胞工程、细胞生物学、抗体工程等课程

代表性论文

1)        Huamin Sun, Xinran Song, Cunjie Li, Qing Li, Shifeng Liu, Ning Deng，Humanized disulfide-stabilized diabody against fibroblast growth factor-2 inhibits PD-L1 expression and epithelial-mesenchymal transition in hepatoma cells through STAT3，IUBMB Life, 2023，75(11)：Pages 957-968,  (SCI三区，IF4.6)，

2)        郭娆晴，黄嘉雯，张利刚，赵文丽，辜江涛，邓宁具有高亲和力和稳定性的人源性抗PD-L1二硫键稳定Diabody的制备，《中国生物工程杂志》，2023，43（6）:20-30

3)        Xi Chen, Ligang Zhang, Wenli Zhao, Raoqing Guo, Ning Deng *.Inhibitory effect of a disulfide stabilized human double chain antibody against bFGF combined with cisplatin on ovarian cancer，International Journal of Sciences，2023-01-03, 2022，9（12）：　88-91，　 ISSN: 1813-4890

4)        J Gu，R Guo，L Zhang，N Deng.Construction of a Natural Human Fab Phage Antibody Library and Screening of Phage Antibody against PD-L1，International Journal of Sciences，2022，11（2）：29-38，Volume 11 - Feb 2022 ，

5)        Simin Zhang, Jiahui Huang, Ligang Zhang, Jiangtao Gu, Qifang Song, Yaxiong Cai, Jiangchuan Zhong, Hui zhong, Yanrui Deng, Wenhui Zhu, Jianfu Zhao, Ning Deng. Fermentation, purification and tumor inhibition of a disulfide-stabilized diabody against fibroblast growth factor-2, Front. Oncol. 4 Jan 2021. (二区，IF6.244)

6)        Chunyan Liu, Ligang Zhang, Wenhui Zhu, Raoqing Guo, Huamin Sun, Xi Chen, Ning Deng*, Barriers and strategies of cationic liposomes for cancer gene therapy, Molecular Therapy: Methods & Clinical Development. （IF6.698），二区,  2020, 18: 751-764  二区.

7)        Wenhui Zhu, Chunyan Liu, Tongyi Lu, Yinmei Zhang, Simin Zhang, Qi Chen, Ning Deng^* . Knockout of EGFL6 by CRISPR/Cas9 mediated inhibition of tumour angiogenesis in ovarian cancer. Frontiers in Oncology.   (IF6.244，二区) 

8)         Ligang Zhang， Chengcheng Jiang， Xi Chen，Jiangtao Gu， Jin-Chen Yu，Qifang Song，Ning Deng* , Large-scale production, purification, and function of a tumor multi-epitope vaccine: Peptibody with bFGF/VEGFA. ENGINEERING IN LIFE SCIENCES. （IF2.734，三区），2020;1-15.

9)        Ligang Zhang, Xi Chen, Yanrui Deng, Chengcheng Jiang, Ning Deng*，Fermentation, purification and immunogenicity of a recombinant tumor T multi-epitope vaccine, VBP3 . Protein Expression and Purification, 2020, 174 : 105658 . （IF 1.6，四区, 

10)     Binhua Wu, Ligang Zhang, Yunfei Yu, Tongyi Lu, Yinmei Zhang, Wenhui Zhu, Qifang Song, Chengding Lv, Jiaying Guo, Yiqiao Tian and Ning Deng*.  miR-6086 inhibits ovarian cancer angiogenesis by downregulating the OC2/VEGFA/EGFL6 axis, Cell Death and Disease (2020)11:345  (二区IF 9.685 )  

11)     Tongyi Lu ，Binhua Wu ，Yunfei Yu ，Wenhui Zhu ，Simin Zhang ，Yinmei Zhang ，Jiaying Guo ，Ning Deng*. Blockade of ONECUT2 expression in ovarian cancer inhibited tumor cell proliferation, migration, invasion and angiogenesis. Cancer Science. 2018 May 8. 109 (7) :2221-2234 （A1 二区， IF 6.7）

12)     Ligang Zhang#, Dan He#, Jianhua Huang#, Yanrui Deng, Ruiqiang Weng, Lei Pan, Ning Deng*, The Immunogenicity and Immunoprotection of VBP3 Multi-epitope Vaccine Targeting Angiogenesis and Tumor Inhibition in Lung Cancer-Bearing Mice, International Journal of Peptide Research and Therapeutics, 2017, 12,

13)     Yaxiong Cai, Shuange Yao, Jiangchuan Zhong, Jinxia Zhang, Haowu Jiang, Yanrui Deng, Ning Deng*. Inhibition activity of a disulfide-stabilized diabody against basic fibroblast growth factor in lung cancer. oncotarget. 2017, Vol. 8, (No. 12), pp: 20187-20197 （A1 一区 IF 5.008）

14)     Yinghua Li,a Zhengfang Lin, Tiantian Xu, Changbing Wang, Mingqi Zhao, Misi Xiao, Hanzhong Wang, Ning Deng* and Bing Zhu*. Delivery of VP1 siRNA to inhibit the EV71 virus using functionalized silver nanoparticles through ROSmediated signaling pathways†. RSC Adv. 2017, 7：1453–1463 （A1 二区，IF3.289）

15)     Yanrui Deng, Hui Liang, Lei Pan, Ruiqiang Weng, Ligang Zhang, Zhitao Wan, Xuejun Lao, Qing Zhang, Likuan Xiong, Ning Deng*. The Polyclonal Antibodies Induced by VBP3 Complex Peptide Targeting Angiogenesis and Tumor Suppression, International Journal of Peptide Research and Therapeutics, 2017,P1-11 （A2 四区 IF 2.191）

16)     Bing Zhu, Tiantian Xu，Zhengfang Lin，Changbing Wang，Yinghua Li，Mingqi Zhao，Liang Hua，Misi Xiao，Ning Deng*，Recombinant heat shock protein 78 enhances enterovirus 71 propagation in Vero cells and is induced in SK-N-SH cells during the infection. Arch Virol. 2017,DOI 10.1007/s00705-017-3287-3 （A2 三区IF2.255）

17)     Yaxiong Cai, Jinxia Zhang, Xuejun Lao, Haowu Jiang, Yunfei Yu, Yanrui Deng, Jiangchuan Zhong, Yiye Liang, Likuan Xiong and Ning Deng*, Construction of a Disulfide-stabilized diabody against FGF-2 and the Inhibition Activity in Targeting Breast Cancer，Cancer Science，2016，2016 , 107 (8) :1141-1150 （A1 二区，IF3.89，）

18)     Ying Liu, Na Huang, Yunfei Yu, Chuping Zheng, Ning Deng* and Jie Liu*. Bioactive SiO2@Ru nanoparticles for osteogenic differentiation of mesenchymal stem cells via activation of Akt signaling pathways, Journal of Materials Chemistry B. 2016,（A1 一区, IF7.571)

19)     Bing Zhu, Yinghua Li, Zhengfang Lin, Mingqi Zhao, Tiantian Xu, Changbing Wang and Ning Deng*. Silver Nanoparticles Induce HePG-2 Cells Apoptosis Through ROS-Mediated Signaling Pathways, Nanoscale Res Lett. 2016 Dec;11(1):198 (A1 二区，IF2.58，)

20)     Shoumei Bai, Patrick Ingram, Yu-Chih Chen, Ning Deng, Alex Pearson, Yashar S.  Niknafs, Patrick O'Hayer, Yun Wang, Zhong-Yin Zhang,  Elisa Boscolo, Joyce Bischoff, Euisik Yoon and Ronald J. Buckanovich, EGFL6 Regulates the Asymmetric Division, Maintenance, and Metastasis of ALDH+Ovarian Cancer Cells. Cancer Res. 2016 Nov1,76(21): 6396-6409.（A1 一区 IF 12.701）

21)     Chuping Zheng，Jinsheng Wang，Yanan Liu,，Qianqian Yu，Ning Deng(*)，Jie Liu(*). Functional Selenium Nanoparticles Enhanced Stem CellOsteoblastic Differentiation through BMP SignalingPathways. Advanced Functional Materials. 2014,24(43): 6872–6883 （A1 一区，IF19.924）

22)     Shi, Cong Ying(#)，Deng, Ning(#)，Liang, Jia Jie，Zhou, Ke Nan，Fu, Qiang Qiang，Tang, Yong(*). A fluorescent polymer dots positive readout fluorescent quenching lateral flow sensor for ractopamine rapid detection，Analytica Chimica Acta，2015，854：202-208。(A1 二区，IF 6.558)

23)     Pan, Lei，Weng, Ruiqiang，Zhang, Jinxia，Wang, Jinsheng，Tang, Yong，Deng, Ning(*). Immune Response of the VEGF/bFGF Complex Peptide Vaccineand Function of Immune Antibodies in Inhibiting Migrationof HUVEC Cells and Proliferation of Cancer Cells.International Journal of Peptide Research and Therapeutics, 2014, 20(4): 565-574 （A2 四区IF2.191）

24)     Yuan, Hailong(#)，Deng, Ning(#)，Zhang, Songmei，Cao, Yange，Wang, Qiong，Liu, Xin，Zhang, Qing(*). The unfolded von Willebrand factor response in bloodstream: the self-association perspective. Journal of Hematology & Oncology. 2012, 5:65-75(A1 二区，IF17.388)